Microsoft Outlook error 0x800C8101 often happens when outgoing mail is blocked, typically due to incorrect SMTP settings, antivirus interference, or corrupted profile components. Here’s a simple fix guide:
- Check SMTP settings – Go to Account Settings in Outlook and verify your Outgoing server (SMTP) address, port, and encryption match your email provider’s requirements.
- Disable antivirus/mail scanning temporarily – Some security tools block Outlook’s connection to SMTP servers. Turn them off just for testing.
- Repair Outlook profile – In Control Panel, navigate to Mail → Show Profiles, select your profile, click Repair, then follow the wizard.
- Clear the Outbox folder – Delete any stuck or large outgoing emails; then try sending a test message.
- Create a new profile – If errors persist, delete or rename your current Outlook profile and set up a new one with your email credentials.
For the full step-by-step solution including screenshots, visit this guide: How to Fix Outlook Error 0x800C8101.